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Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model
Mitochondria are vital organelles inside the cell and contribute to intracellular calcium (Ca(2+)) dynamics directly and indirectly via calcium exchange, ATP generation, and production of reactive oxygen species (ROS). Arrhythmogenic Ca(2+) alternans in cardiac myocytes has been observed in experime...
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| Gepubliceerd in: | PLoS Comput Biol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7861552/ https://ncbi.nlm.nih.gov/pubmed/33493168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008624 |
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