Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

BACKGROUND: Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral density are able to predict the risk of osteopo...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Lu, Tianyuan, Forgetta, Vincenzo, Keller-Baruch, Julyan, Nethander, Maria, Bennett, Derrick, Forest, Marie, Bhatnagar, Sahir, Walters, Robin G., Lin, Kuang, Chen, Zhengming, Li, Liming, Karlsson, Magnus, Mellström, Dan, Orwoll, Eric, McCloskey, Eugene V., Kanis, John A., Leslie, William D., Clarke, Robert J., Ohlsson, Claes, Greenwood, Celia M. T., Richards, J. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860212/
https://ncbi.nlm.nih.gov/pubmed/33536041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00838-6
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