Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes

BACKGROUND: Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide an opportunity to understand risk factors since they reflect etiologic pathways from the entire genome. We therefore tested whether...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cardiovasc Diabetol
Prif Awduron: Lu, Tianyuan, Forgetta, Vincenzo, Yu, Oriana H. Y., Mokry, Lauren, Gregory, Madeline, Thanassoulis, George, Greenwood, Celia M. T., Richards, J. Brent
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Original Investigation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993460/
https://ncbi.nlm.nih.gov/pubmed/32000781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-020-0988-9
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