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Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes

BACKGROUND: Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide an opportunity to understand risk factors since they reflect etiologic pathways from the entire genome. We therefore tested whether...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Lu, Tianyuan, Forgetta, Vincenzo, Yu, Oriana H. Y., Mokry, Lauren, Gregory, Madeline, Thanassoulis, George, Greenwood, Celia M. T., Richards, J. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993460/
https://ncbi.nlm.nih.gov/pubmed/32000781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-020-0988-9
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