Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1) overexpression reduces APP processing and increases alpha- versus beta-secretase activity, in vitro

The organic anion transporter Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1), also known as MRP1, has been demonstrated in murine models of Alzheimer's disease (AD) to export amyloid beta (Abeta) from the endothelial cells of the blood–brain barrier to the periphery, and t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biol Open
Main Authors: Jepsen, Wayne M., De Both, Matthew, Siniard, Ashley L., Ramsey, Keri, Piras, Ignazio S., Naymik, Marcus, Henderson, Adrienne, Huentelman, Matthew J.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists Ltd 2021
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860133/
https://ncbi.nlm.nih.gov/pubmed/32878879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.054627
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