A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference

Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease. Its development and progression depend on genetically predisposed susceptibility of the patient towards several ‘hits’ that induce fat storage first and later inflammation and fibrosis. Here, we differentiated induced pluripotent...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biol Open
Päätekijät: Graffmann, Nina, Ncube, Audrey, Martins, Soraia, Fiszl, Aurelian Robert, Reuther, Philipp, Bohndorf, Martina, Wruck, Wasco, Beller, Mathias, Czekelius, Constantin, Adjaye, James
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Ltd 2021
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860118/
https://ncbi.nlm.nih.gov/pubmed/33372064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.054189
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