A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference

Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease. Its development and progression depend on genetically predisposed susceptibility of the patient towards several ‘hits’ that induce fat storage first and later inflammation and fibrosis. Here, we differentiated induced pluripotent...

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Publicat a:Biol Open
Autors principals: Graffmann, Nina, Ncube, Audrey, Martins, Soraia, Fiszl, Aurelian Robert, Reuther, Philipp, Bohndorf, Martina, Wruck, Wasco, Beller, Mathias, Czekelius, Constantin, Adjaye, James
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860118/
https://ncbi.nlm.nih.gov/pubmed/33372064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.054189
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