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High throughput screening to identify inhibitors of the type I interferon – major histocompatibility complex class I pathway in skeletal muscle

Immunosuppressants used to treat autoimmunity are often not curative and have many side effects. Our purpose was to identify therapeutics for autoimmunity of the skeletal muscle termed idiopathic inflammatory myopathies (myositis). Recent evidence shows the pro-inflammatory type I interferons (IFN)...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Kinder, Travis B., Dranchak, Patricia K., Inglese, James
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859889/
https://ncbi.nlm.nih.gov/pubmed/32459468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00343
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