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High throughput screening to identify inhibitors of the type I interferon – major histocompatibility complex class I pathway in skeletal muscle
Immunosuppressants used to treat autoimmunity are often not curative and have many side effects. Our purpose was to identify therapeutics for autoimmunity of the skeletal muscle termed idiopathic inflammatory myopathies (myositis). Recent evidence shows the pro-inflammatory type I interferons (IFN)...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7859889/ https://ncbi.nlm.nih.gov/pubmed/32459468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00343 |
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