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LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma

Leucine zipper/EF hand-containing transmembrane-1 (LETM1) is an inner mitochondrial membrane protein that has been reported to be involved in many primary tumors and may regulate many biological processes. However, the biological role and molecular mechanism of LETM1 in the progression of hepatocell...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Zhou, Baoyong, Yang, Changhong, Yan, Xiong, Shi, Zhengrong, Xiao, Heng, Wei, Xufu, Jiang, Ning, Wu, Zhongjun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859436/
https://ncbi.nlm.nih.gov/pubmed/33552978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.606790
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