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LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma

Leucine zipper/EF hand-containing transmembrane-1 (LETM1) is an inner mitochondrial membrane protein that has been reported to be involved in many primary tumors and may regulate many biological processes. However, the biological role and molecular mechanism of LETM1 in the progression of hepatocell...

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Vydáno v:Front Oncol
Hlavní autoři: Zhou, Baoyong, Yang, Changhong, Yan, Xiong, Shi, Zhengrong, Xiao, Heng, Wei, Xufu, Jiang, Ning, Wu, Zhongjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859436/
https://ncbi.nlm.nih.gov/pubmed/33552978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.606790
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