Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury

After complete spinal cord injuries (SCI), spinal segments below the lesion maintain inter-segmental communication via the intraspinal propriospinal network. However, it is unknown whether selective manipulation of these circuits can restore locomotor function in the absence of brain-derived inputs....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Brommer, Benedikt, He, Miao, Zhang, Zicong, Yang, Zhiyun, Page, Jessica C., Su, Junfeng, Zhang, Yu, Zhu, Junjie, Gouy, Emilia, Tang, Jing, Williams, Philip, Dai, Wei, Wang, Qi, Solinsky, Ryan, Chen, Bo, He, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859413/
https://ncbi.nlm.nih.gov/pubmed/33536416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-20980-4
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