Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations

Many human spinal cord injuries are anatomically incomplete, but exhibit complete paralysis. It is unknown why spared axons fail to mediate functional recovery in these cases. To investigate this, we undertook a small-molecule screen in mice with staggered bilateral hemisections, in which the lumbar...

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Vydáno v:Cell
Hlavní autoři: Chen, Bo, Li, Yi, Yu, Bin, Zhang, Zicong, Brommer, Benedikt, Williams, Philip Raymond, Liu, Yuanyuan, Hegarty, Shane Vincent, Zhou, Songlin, Zhu, Junjie, Guo, Hong, Lu, Yi, Gu, Xiaosong, He, Zhigang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063786/
https://ncbi.nlm.nih.gov/pubmed/30033363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.005
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