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Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations

Many human spinal cord injuries are anatomically incomplete, but exhibit complete paralysis. It is unknown why spared axons fail to mediate functional recovery in these cases. To investigate this, we undertook a small-molecule screen in mice with staggered bilateral hemisections, in which the lumbar...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Chen, Bo, Li, Yi, Yu, Bin, Zhang, Zicong, Brommer, Benedikt, Williams, Philip Raymond, Liu, Yuanyuan, Hegarty, Shane Vincent, Zhou, Songlin, Zhu, Junjie, Guo, Hong, Lu, Yi, Gu, Xiaosong, He, Zhigang
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063786/
https://ncbi.nlm.nih.gov/pubmed/30033363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.005
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