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Conserved strategies of RNA polymerase I hibernation and activation

RNA polymerase (Pol) I transcribes the ribosomal RNA precursor in all eukaryotes. The mechanisms ‘activation by cleft contraction’ and ‘hibernation by dimerization’ are unique to the regulation of this enzyme, but structure-function analysis is limited to baker’s yeast. To understand whether regulat...

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Pubblicato in:Nat Commun
Autori principali: Heiss, Florian B., Daiß, Julia L., Becker, Philipp, Engel, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859239/
https://ncbi.nlm.nih.gov/pubmed/33536435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21031-8
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