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RNA polymerase I (Pol I) passage through nucleosomes depends on Pol I subunits binding its lobe structure

RNA polymerase I (Pol I) is a highly efficient enzyme specialized in synthesizing most ribosomal RNAs. After nucleosome deposition at each round of rDNA replication, the Pol I transcription machinery has to deal with nucleosomal barriers. It has been suggested that Pol I–associated factors facilitat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Merkl, Philipp E., Pilsl, Michael, Fremter, Tobias, Schwank, Katrin, Engel, Christoph, Längst, Gernot, Milkereit, Philipp, Griesenbeck, Joachim, Tschochner, Herbert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152749/
https://ncbi.nlm.nih.gov/pubmed/32060094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011827
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