TOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA production

Ribosome biogenesis is tightly linked to cellular growth. A crucial step in the regulation of ribosomal RNA (rRNA) gene transcription is the formation of the complex between RNA polymerase I (Pol I) and the Pol I-dependent transcription factor Rrn3p. We found that TOR inactivation leads to proteasom...

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Hlavní autoři: Philippi, Anja, Steinbauer, Robert, Reiter, Alarich, Fath, Stephan, Leger-Silvestre, Isabelle, Milkereit, Philipp, Griesenbeck, Joachim, Tschochner, Herbert
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938223/
https://ncbi.nlm.nih.gov/pubmed/20421203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq264
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