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CD39(+)PD-1(+)CD8(+) T cells mediate metastatic dormancy in breast cancer

Some breast tumors metastasize aggressively whereas others remain dormant for years. The mechanism governing metastatic dormancy remains largely unknown. Through high-parametric single-cell mapping in mice, we identify a discrete population of CD39(+)PD-1(+)CD8(+) T cells in primary tumors and in do...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Tallón de Lara, Paulino, Castañón, Héctor, Vermeer, Marijne, Núñez, Nicolás, Silina, Karina, Sobottka, Bettina, Urdinez, Joaquín, Cecconi, Virginia, Yagita, Hideo, Movahedian Attar, Farkhondeh, Hiltbrunner, Stefanie, Glarner, Isabelle, Moch, Holger, Tugues, Sònia, Becher, Burkhard, van den Broek, Maries
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859213/
https://ncbi.nlm.nih.gov/pubmed/33536445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21045-2
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