Inter-cellular transmission of hepatic ER stress in obesity disrupts systemic metabolism

Endoplasmic reticulum stress (ERS) has a pathophysiological role in obesity-associated insulin resistance. Yet, the coordinated tissue response to ERS remains unclear. Increased connexin (Cx)43-mediated intercellular communication, has been implicated in tissue adaptive and maladaptive response to v...

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Publicat a:Cell Metab
Autors principals: Tirosh, Amir, Tuncman, Gurol, Calay, Ediz S., Rathaus, Moran, Ron, Idit, Tirosh, Amit, Yalcin, Abdullah, Lee, Yankun G, Livne, Rinat, Ron, Sophie, Minsky, Neri, Arruda, Ana Paula, Hotamisligil, Gökhan S.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858244/
https://ncbi.nlm.nih.gov/pubmed/33340456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.11.009
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