Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase

Mammalian target of rapamycin complex 1 (TORC1) is controlled by the GATOR complex composed of the GATOR1 subcomplex and its inhibitor, the GATOR2 subcomplex, sensitive to amino acid starvation. Previously, we identified fission yeast GATOR1 that prevents deregulated activation of TORC1 (Chia et al....

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Fukuda, Tomoyuki, Sofyantoro, Fajar, Tai, Yen Teng, Chia, Kim Hou, Matsuda, Takato, Murase, Takaaki, Morozumi, Yuichi, Tatebe, Hisashi, Kanki, Tomotake, Shiozaki, Kazuhiro
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857730/
https://ncbi.nlm.nih.gov/pubmed/33534698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60969
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