Association between sperm mitochondarial DNA copy number and nuclear DNA methylation

AIM: Accumulating evidence associates sperm mitochondria DNA copy number (mtDNAcn) with male infertility and reproductive success. However, the mechanism underlying mtDNAcn variation is largely unknown. PATIENTS & METHODS: Sperm mtDNAcn and genome-wide DNA methylation were assessed using triplex...

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Publicado en:Epigenomics
Autores principales: Oluwayiose, Oladele A, Josyula, Srinihaari, Houle, Emily, Marcho, Chelsea, Whitcomb, Brian W, Rahil, Tayyab, Sites, Cynthia K, Pilsner, J Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: Future Medicine Ltd 2020
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857360/
https://ncbi.nlm.nih.gov/pubmed/33320694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2020-0253
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