Associations of sperm mitochondrial DNA copy number and deletion rate with fertilization and embryo development in a clinical setting

STUDY QUESTION: Are sperm mitochondrial DNA copy number (mtDNAcn) and deletion rate (mtDNAdel) associated with odds of fertilization and high embryo quality at Days 3 and 5? SUMMARY ANSWER: Higher sperm mtDNAcn and mtDNAdel were associated with lower odds of high quality Day 3 embryos and transfer q...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Wu, Haotian, Whitcomb, Brian W, Huffman, Alexandra, Brandon, Nicole, Labrie, Suzanne, Tougias, Ellen, Lynch, Kelly, Rahil, Tayyab, Sites, Cynthia K, Pilsner, J Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295960/
https://ncbi.nlm.nih.gov/pubmed/30428043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dey330
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