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Positron Emission Tomography Imaging of Functional TGFβ Activity and Benefit of TGFβ Inhibition in Irradiated Intracranial Tumors
INTRODUCTION: Transforming growth factor β (TGFβ) promotes cell survival by endorsing DNA damage repair and mediates an immunosuppressive tumor microenvironment. Thus, TGFβ activation in response to radiation therapy is potentially targetable because it opposes therapeutic control. Strategies to ass...
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| Опубликовано в: : | Int J Radiat Oncol Biol Phys |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856163/ https://ncbi.nlm.nih.gov/pubmed/33007434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.09.043 |
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