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Mediation Effect Selection in High-Dimensional and Compositional Microbiome Data

The microbiome plays an important role in human health by mediating the path from environmental exposures to health outcomes. The relative abundances of the high-dimensional microbiome data have an unit-sum restriction, rendering standard statistical methods in the Euclidean space invalid. To addres...

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Bibliographic Details
Published in:Stat Med
Main Authors: Zhang, Haixiang, Chen, Jun, Feng, Yang, Wang, Chan, Li, Huilin, Liu, Lei
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855955/
https://ncbi.nlm.nih.gov/pubmed/33205470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8808
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