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Testing for mediation effect with application to human microbiome data

Mediation analysis has been commonly used to study the effect of an exposure on an outcome through a mediator. In this paper, we are interested in exploring the mediation mechanism of microbiome, whose special features make the analysis challenging. We consider the isometric logratio transformation...

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Publicat a:Stat Biosci
Autors principals: Zhang, Haixiang, Chen, Jun, Li, Zhigang, Liu, Lei
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177450/
https://ncbi.nlm.nih.gov/pubmed/34093887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-019-09253-3
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