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MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment

The majority of human colorectal cancer remains resistant to immune checkpoint inhibitor (ICI) immunotherapy, but the underlying mechanism is incompletely understood. We report here that MS4A1, the gene encoding B cell surface marker CD20, is significantly downregulated in human colorectal carcinoma...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Mudd, T William, Lu, Chunwan, Klement, John D., Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855947/
https://ncbi.nlm.nih.gov/pubmed/33352466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104260
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