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Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Exposure to alkylanilines found in tobacco smoke and indoor air is associated with risk of bladder cancer. Genetic factors significantly influence the metabolism of arylamine carcinogens and the toxicological outcomes that result from exposure. We utilized nucleotide excision repair (NER) - deficien...

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Foilsithe in:Arch Toxicol
Main Authors: Leggett, Carmine S., Doll, Mark A., States, J. Christopher, Hein, David W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855884/
https://ncbi.nlm.nih.gov/pubmed/33136180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02901-4
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