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Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Exposure to alkylanilines found in tobacco smoke and indoor air is associated with risk of bladder cancer. Genetic factors significantly influence the metabolism of arylamine carcinogens and the toxicological outcomes that result from exposure. We utilized nucleotide excision repair (NER) - deficien...

詳細記述

保存先:
書誌詳細
出版年:Arch Toxicol
主要な著者: Leggett, Carmine S., Doll, Mark A., States, J. Christopher, Hein, David W.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855884/
https://ncbi.nlm.nih.gov/pubmed/33136180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02901-4
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