Folate-dependent hydrolysis of acetyl-coenzyme A by recombinant human and rodent arylamine N-acetyltransferases

Arylamine N-acetyltransferases (NATs) are drug and xenobiotic metabolizing enzymes that catalyze the N-acetylation of arylamines and hydrazines and the O-acetylation of N-hydroxy-arylamines. Recently, studies report that human NAT1 and mouse Nat2 hydrolyze acetyl-coenzyme A (AcCoA) into acetate and...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Stepp, Marcus W., Mamaliga, Galina, Doll, Mark A., States, J. Christopher, Hein, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545580/
https://ncbi.nlm.nih.gov/pubmed/26309907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.07.011
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