Phenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-Dependent

Human arylamine N-acetyltransferase 1 (NAT1) is a phase II cytosolic enzyme responsible for the activation or deactivation of many arylamine compounds including pharmaceuticals and environmental carcinogens. NAT1 is highly polymorphic and has been associated with altered risk toward many cancers. NA...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Millner, Lori M., Doll, Mark A., Cai, Jian, States, J. Christopher, Hein, David W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2012
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250052/
https://ncbi.nlm.nih.gov/pubmed/22010219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.041855
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk