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Structural and functional characterization of the Spo11 core complex

Spo11, which makes DNA double-strand breaks (DSBs) essential for meiotic recombination, has long been recalcitrant to biochemical study. We provide molecular analysis of S. cerevisiae Spo11 purified with partners Rec102, Rec104 and Ski8. Rec102 and Rec104 jointly resemble the B subunit of archaeal T...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Claeys Bouuaert, Corentin, Tischfield, Sam E., Pu, Stephen, Mimitou, Eleni P., Arias-Palomo, Ernesto, Berger, James M., Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855791/
https://ncbi.nlm.nih.gov/pubmed/33398171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00534-w
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