CSF1R Inhibition Depletes Tumor-Associated Macrophages and Attenuates Tumor Progression in a Mouse Sonic Hedgehog-Medulloblastoma Model

The immune microenvironment of tumors can play a critical role in promoting or inhibiting tumor progression depending on the context. We present evidence that tumor-associated macrophages/microglia (TAMs) can promote tumor progression in the sonic hedgehog subgroup of medulloblastoma (SHH-MB). By co...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Tan, I-Li, Arifa, Raquel Duque Nascimento, Rallapalli, Harikrishna, Kana, Veronika, Lao, Zhimin, Sanghrajka, Reeti Mayur, Bayin, N. Sumru, Tanne, Antoine, Wojcinski, Alexandre, Korshunov, Andrey, Bhardwaj, Nina, Merad, Miriam, Turnbull, Daniel H., Lafaille, Juan J., Joyner, Alexandra L
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855734/
https://ncbi.nlm.nih.gov/pubmed/33159168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01536-0
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