Integration of multi-omic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer

Clinical trial results have recently demonstrated that inhibiting inflammation by targeting the interleukin-1β pathway can offer a significant reduction in lung cancer incidence and mortality, highlighting a pressing and unmet need to understand the benefits of inflammation-focused lung cancer thera...

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Udgivet i:Genet Epidemiol
Main Authors: Sun, Ryan, Xu, Miao, Li, Xihao, Gaynor, Sheila, Zhou, Hufeng, Li, Zilin, Bossé, Yohan, Lam, Stephen, Tsao, Ming-Sound, Tardon, Adonina, Chen, Chu, Doherty, Jennifer, Goodman, Gary, Bojesen, Stig Egil, Landi, Maria Teresa, Johansson, Mattias, Field, John K., Bickeböller, Heike, Wichmann, H-Erich, Risch, Angela, Rennert, Gadi, Arnold, Suzanne, Wu, Xifeng, Melander, Olle, Brunnström, Hans, Le Marchand, Loic, Liu, Geoffrey, Andrew, Angeline, Duell, Eric, Kiemeney, Lambertus A., Shen, Hongbing, Haugen, Aage, Johansson, Mikael, Grankvist, Kjell, Caporaso, Neil, Woll, Penella, Teare, M. Dawn, Scelo, Ghislaine, Hong, Yun-Chul, Yuan, Jian-Min, Lazarus, Philip, Schabath, Matthew B., Aldrich, Melinda C., Albanes, Demetrios, Mak, Raymond, Barbie, David, Brennan, Paul, Hung, Rayjean J., Amos, Christopher I., Christiani, David C., Lin, Xihong
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855632/
https://ncbi.nlm.nih.gov/pubmed/32924180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22358
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