Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

BACKGROUND: Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to assess causality, may help to identify the metabolic drivers of lung cancer....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carreras-Torres, Robert, Johansson, Mattias, Haycock, Philip C., Wade, Kaitlin H., Relton, Caroline L., Martin, Richard M., Davey Smith, George, Albanes, Demetrius, Aldrich, Melinda C., Andrew, Angeline, Arnold, Susanne M., Bickeböller, Heike, Bojesen, Stig E., Brunnström, Hans, Manjer, Jonas, Brüske, Irene, Caporaso, Neil E., Chen, Chu, Christiani, David C., Christian, W. Jay, Doherty, Jennifer A., Duell, Eric J., Field, John K., Davies, Michael P. A., Marcus, Michael W., Goodman, Gary E., Grankvist, Kjell, Haugen, Aage, Hong, Yun-Chul, Kiemeney, Lambertus A., van der Heijden, Erik H. F. M., Kraft, Peter, Johansson, Mikael B., Lam, Stephen, Landi, Maria Teresa, Lazarus, Philip, Le Marchand, Loïc, Liu, Geoffrey, Melander, Olle, Park, Sungshim L., Rennert, Gad, Risch, Angela, Haura, Eric B., Scelo, Ghislaine, Zaridze, David, Mukeriya, Anush, Savić, Milan, Lissowska, Jolanta, Swiatkowska, Beata, Janout, Vladimir, Holcatova, Ivana, Mates, Dana, Schabath, Matthew B., Shen, Hongbing, Tardon, Adonina, Teare, M Dawn, Woll, Penella, Tsao, Ming-Sound, Wu, Xifeng, Yuan, Jian-Min, Hung, Rayjean J., Amos, Christopher I., McKay, James, Brennan, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464539/
https://ncbi.nlm.nih.gov/pubmed/28594918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177875
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