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Characterizing the effect of background selection on the polygenicity of brain-related traits
BACKGROUND: Genome-wide association studies (GWAS) have demonstrated that psychopathology phenotypes are affected by many risk alleles with small effect (polygenicity). It is unclear how ubiquitously evolutionary pressures influence the genetic architecture of these traits. METHODS: We partitioned S...
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| 出版年: | Genomics |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855394/ https://ncbi.nlm.nih.gov/pubmed/33278486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2020.11.032 |
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