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Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors

The P2X7 receptor (P2X7R) is an ATP-gated cation channel with a critical role in many physiological and pathological processes, and shows prominent functional differences across mammalian species, exemplified by larger current responses of the rat (r) P2X7R to ATP and its analogue BzATP and a greate...

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Detalles Bibliográficos
Publicado en:Purinergic Signal
Main Authors: Caseley, Emily A, Muench, Stephen P, Jiang, Lin-Hua
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855165/
https://ncbi.nlm.nih.gov/pubmed/33029714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09730-1
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