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Conformational changes during human P2X7 receptor activation examined by structural modelling and cysteine-based cross-linking studies
The P2X7 receptor (P2X7R) is important in mediating a range of physiological functions and pathologies associated with tissue damage and inflammation and represents an attractive therapeutic target. However, in terms of their structure-function relationships, the mammalian P2X7Rs remain poorly chara...
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| Vydáno v: | Purinergic Signal |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Netherlands
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5334206/ https://ncbi.nlm.nih.gov/pubmed/28025718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9553-0 |
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