Non-Synonymous Single Nucleotide Polymorphisms in the P2X Receptor Genes: Association with Diseases, Impact on Receptor Functions and Potential Use as Diagnosis Biomarkers

P2X receptors are Ca(2+)-permeable cationic channels in the cell membranes, where they play an important role in mediating a diversity of physiological and pathophysiological functions of extracellular ATP. Mammalian cells express seven P2X receptor genes. Single nucleotide polymorphisms (SNPs) are...

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Hlavní autoři: Caseley, Emily A., Muench, Stephen P., Roger, Sebastien, Mao, Hong-Ju, Baldwin, Stephen A., Jiang, Lin-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159798/
https://ncbi.nlm.nih.gov/pubmed/25079442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150813344
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