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YY1 Interacts with Guanine Quadruplexes to Regulate DNA Looping and Gene Expression
The DNA guanine quadruplexes (G4) play important roles in multiple cellular processes, including DNA replication, transcription and maintenance of genome stability. Here, we showed that Yin Yang-1 (YY1) can bind directly to G4 structures. ChIP-Seq results revealed that YY1 binding sites overlap exte...
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| Gepubliceerd in: | Nat Chem Biol |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854983/ https://ncbi.nlm.nih.gov/pubmed/33199912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00695-1 |
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