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HIV Impairs Alveolar Macrophage Function Via MicroRNA-144-Induced Suppression of Nrf2

RATIONALE: Despite anti-retroviral therapy, HIV-1 infection increases the risk of pneumonia and causes oxidative stress and defective alveolar macrophage (AM) immune function. We have previously determined that HIV-1 proteins inhibit antioxidant defenses and impair AM phagocytosis by suppressing nuc...

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Bibliografiske detaljer
Udgivet i:Am J Med Sci
Main Authors: Fan, Xian, Murray, Shannon C., Staitieh, Bashar S., Spearman, Paul, Guidot, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854972/
https://ncbi.nlm.nih.gov/pubmed/32773107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjms.2020.07.026
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