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Nrf2 regulates PU.1 expression and activity in the alveolar macrophage

Alveolar macrophage (AM) immune function depends on the activation of the transcription factor PU.1 by granulocyte macrophage colony-stimulating factor. We have determined that chronic alcohol ingestion dampens PU.1 signaling via an unknown zinc-dependent mechanism; specifically, although PU.1 is no...

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書目詳細資料
發表在:Am J Physiol Lung Cell Mol Physiol
Main Authors: Staitieh, Bashar S., Fan, Xian, Neveu, Wendy, Guidot, David M.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437011/
https://ncbi.nlm.nih.gov/pubmed/25840997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00355.2014
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