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MiR-144 mediates Nrf2 inhibition and alveolar epithelial dysfunction in HIV-1 transgenic rats

Chronic HIV infection causes redox stress and increases the risk of acute and chronic lung injury, even when individuals are adherent to antiretroviral therapy. HIV-1 transgene expression in rats inhibits nuclear factor (erythroid-derived 2)-like 2 (Nrf2), which regulates antioxidant defenses and al...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Kukoyi, Abiodun T., Fan, Xian, Staitieh, Bashar S., Hybertson, Brooks M., Gao, Bifeng, McCord, Joe M., Guidot, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732420/
https://ncbi.nlm.nih.gov/pubmed/31091144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00038.2019
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