Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution

The heterogeneous nature of tumour microenvironment (TME) underlying diverse treatment responses remains unclear in nasopharyngeal carcinoma (NPC). Here, we profile 176,447 cells from 10 NPC tumour-blood pairs, using single-cell transcriptome coupled with T cell receptor sequencing. Our analyses rev...

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Pubblicato in:Nat Commun
Autori principali: Liu, Yang, He, Shuai, Wang, Xi-Liang, Peng, Wan, Chen, Qiu-Yan, Chi, Dong-Mei, Chen, Jie-Rong, Han, Bo-Wei, Lin, Guo-Wang, Li, Yi-Qi, Wang, Qian-Yu, Peng, Rou-Jun, Wei, Pan-Pan, Guo, Xiang, Li, Bo, Xia, Xiaojun, Mai, Hai-Qiang, Hu, Xue-Da, Zhang, Zemin, Zeng, Yi-Xin, Bei, Jin-Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854640/
https://ncbi.nlm.nih.gov/pubmed/33531485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21043-4
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