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Unraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses

Currently, there is no strong evidence of the well-established biomarkers for immune checkpoint inhibitors (ICIs) in nasopharyngeal carcinoma (NPC). Here, we aimed to reveal the heterogeneity of tumour microenvironment (TME) through virtual microdissection of gene expression profiles. An immune-enri...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Chen, Yu-Pei, Lv, Jia-Wei, Mao, Yan-Ping, Li, Xiao-Min, Li, Jun-Yan, Wang, Ya-Qin, Xu, Cheng, Li, Ying-Qin, He, Qing-Mei, Yang, Xiao-Jing, Lei, Yuan, Shen, Jia-Yi, Tang, Ling-Long, Chen, Lei, Zhou, Guan-Qun, Li, Wen-Fei, Du, Xiao-Jing, Guo, Rui, Liu, Xu, Zhang, Yuan, Zeng, Jing, Yun, Jing-Ping, Sun, Ying, Liu, Na, Ma, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7798236/
https://ncbi.nlm.nih.gov/pubmed/33430876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01292-5
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