Pancreatic ductal adenocarcinoma immune microenvironment and immunotherapy prospects

The tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) is non-immunogenic, which consists of the stellate cells, fibroblasts, immune cells, extracellular matrix, and some other immune suppressive molecules. This low tumor perfusion microenvironment with physical dense fibrotic stroma...

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Bibliographic Details
Published in:Chronic Dis Transl Med
Main Authors: Li, Ke-Yu, Yuan, Jia-Long, Trafton, Diego, Wang, Jian-Xin, Niu, Nan, Yuan, Chun-Hui, Liu, Xu-Bao, Zheng, Lei
Format: Artigo
Language:Inglês
Published: Chinese Medical Association 2020
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096327/
https://ncbi.nlm.nih.gov/pubmed/32226930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cdtm.2020.01.002
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