Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution

The heterogeneous nature of tumour microenvironment (TME) underlying diverse treatment responses remains unclear in nasopharyngeal carcinoma (NPC). Here, we profile 176,447 cells from 10 NPC tumour-blood pairs, using single-cell transcriptome coupled with T cell receptor sequencing. Our analyses rev...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Liu, Yang, He, Shuai, Wang, Xi-Liang, Peng, Wan, Chen, Qiu-Yan, Chi, Dong-Mei, Chen, Jie-Rong, Han, Bo-Wei, Lin, Guo-Wang, Li, Yi-Qi, Wang, Qian-Yu, Peng, Rou-Jun, Wei, Pan-Pan, Guo, Xiang, Li, Bo, Xia, Xiaojun, Mai, Hai-Qiang, Hu, Xue-Da, Zhang, Zemin, Zeng, Yi-Xin, Bei, Jin-Xin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854640/
https://ncbi.nlm.nih.gov/pubmed/33531485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21043-4
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