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An update of cyclic nucleotide phosphodiesterase as a target for cardiac diseases

INTRODUCTION---: Cyclic nucleotides, cAMP and cGMP, are important second messengers of intracellular signaling and play crucial roles in cardiovascular biology and diseases. Cyclic nucleotide phosphodiesterases (PDEs) control the duration, magnitude, and compartmentalization of cyclic nucleotide sig...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Discov
Main Authors: Chen, Si, Yan, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854486/
https://ncbi.nlm.nih.gov/pubmed/32957823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2020.1821643
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