Reshaping the Immune Microenvironment by Oncolytic Herpes Simplex Virus in Murine Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the major type of pancreatic malignancy with very poor prognosis. Despite the promising results of immune checkpoint inhibitors (ICIs) in some solid tumors, immunotherapy is less effective for PDAC due to its immunosuppressive tumor microenvironment (TME)....

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發表在:Mol Ther
Main Authors: Zhang, Liming, Wang, Wei, Wang, Ruikun, Zhang, Nianchao, Shang, Hang, Bi, Yang, Chen, Da, Zhang, Cuizhu, Li, Long, Yin, Jie, Zhang, Hongkai, Cao, Youjia
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2021
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854309/
https://ncbi.nlm.nih.gov/pubmed/33130310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.10.027
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