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TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα
NF-κB signaling plays a critical role in tumor growth and treatment resistance in GBM as in many other cancers. However, the molecular mechanisms underlying high, constitutive NF-κB activity in GBM remains to be elucidated. Here, we screened a panel of tripartite motif (TRIM) family proteins and ide...
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| izdano v: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7853150/ https://ncbi.nlm.nih.gov/pubmed/32814880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00606-w |
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