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Bcl10 is required for the development and suppressive function of Foxp3(+) regulatory T cells
Foxp3(+) regulatory T (Treg) cells play a critical role in peripheral tolerance. Bcl10, acting as a scaffolding protein in the Carma1-Bcl10-Malt1 (CBM) complex, has a critical role in TCR-induced signaling, leading to NF-κB activation and is required for T-cell activation. The role of Bcl10 in conve...
में बचाया:
| में प्रकाशित: | Cell Mol Immunol |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7853095/ https://ncbi.nlm.nih.gov/pubmed/31595055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0297-y |
| टैग : |
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