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Sodium chloride inhibits the suppressive function of FOXP3(+) regulatory T cells
FOXP3(+) Tregs are central for the maintenance of self-tolerance and can be defective in autoimmunity. In multiple sclerosis and type-1 diabetes, dysfunctional self-tolerance is partially mediated by a population of IFNγ-secreting Tregs. It was previously reported that increased NaCl concentrations...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4639983/ https://ncbi.nlm.nih.gov/pubmed/26524592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81151 |
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