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Conversion of effector CD4(+) T cells to a CD8(+) MHC II-recognizing lineage
CD4(+) and CD8(+) T cells are dichotomous lineages in adaptive immunity. While conventionally viewed as distinct fates that are fixed after thymic development, accumulating evidence indicates that these two populations can exhibit significant lineage plasticity, particularly upon TCR-mediated activa...
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| 發表在: | Cell Mol Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7853072/ https://ncbi.nlm.nih.gov/pubmed/32066854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0347-5 |
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